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KMID : 0870420100140010001
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2010 Volume.14 No. 1 p.1 ~ p.9
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The Discriminating Ability of a Prognosis According to the TNM, Okuda, CLIP, JIS, and BCLC Staging Systems for Hepatocellular Carcinoma
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Koo Hye-Young
Kwon Sung-Won
Lee Hwa-Young
Hwang Sung-Kyu
Lim Gyu-Sung
Kim Man-Deuk
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Abstract
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Purpose: There is yet no ideal single staging system for hepatocellular carcinoma (HCC). The aim of this study was to analyze HCC survival times according to the TNM, Okuda, CLIP, JIS, and BCLC staging systems and their prognostic discrimination ability.
Methods: A retrospective analysis of medical records and statistical data from the Korean statistical information service was done for HCC patients diagnosed at Bundang CHA hospital between June, 1992 and February, 2009.
Results: During follow-up, 121 (72%) of 168 people died and 1, 3 and 5 year overall survival rates were, respectively, 58%, 35% and 25%. In the analysis of discriminative ability of each staging system, the CLIP staging system showed the highest LR X2 value, and the lowest AIC value (p＜0.05). Therefore, the CLIP staging system appears to be superior to the other systems.
Conclusion: Of the 5 staging systems in this study, the CLIP staging system was superior to the other systems, but the results of many other studies from different countries have varied. It is necessary to establish the staging system suitable for each country’s actual circumstances.
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KEYWORD
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Hepatocellular carcinoma, Staging system, Survival analysis, Prognosis
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